EPISODES OF SYMPTOMATIC HYPOTENSION IN PATIENTS WITH CARDIOVASCULAR DISEASE AND IN HEALTHY
INDIVIDUALS, DEPENDING ON THE CLINICAL CHARACTERISTICS AND RISK FACTORS 

Ermasova Svetlana Aleksandrovna, Assistant, sub-department of faculty therapy, Saratov State Medical University named after V. I. Razumosky (137 Bolshaya Sadovaya street, Saratov, Russia), E-mail: sver4@yandex.ru
Shvarts Yuriy Grigor'evich, Doctor of medical sciences, professor, head of sub-department of faculty therapy, Saratov State Medical University named after V. I. Razumosky (137 Bolshaya Sadovaya street, Saratov, Russia), E-mail: shwartz58@yandex.ru 

616.12-008.331.1 

10.21685/2072-3032-2019-2-2 

Background. The goal of the paper is to analyze the frequency of episodes of symptomatic hypotension in patients with hypertension, cardiovascular disease and in healthy individuals, to identify possible relationships with cardiovascular risk factors, with the presence of cardiovascular diseases, as well as with ongoing antihypertensive therapy.
Material and Methods. The study included 269 people aged from 40 to 80 years, which included relatives of university students, according to its characteristics the sample was representative of the adult population of the city, as well as 150 patients of therapeutic and cardiological hospital with hypertension and / or other cardiovascular disease. The presence of symptomatic hypotensive episodes was determined according to a survey of patients. We also used the modified questionnaire Howard and Rose.
Results. Symptomatic hypotensive episodes in healthy relatives of the students are found in 49.6 % of individuals, in those who suffered from hypertension are found in 51.5 % (p < 0.05). In the group of hospitalized patients, most of them have hypertension, symptomatic hypotension was seen in 60.7 % of cases (p < 0.05). Among all persons with arterial hypertension in stroke patients, 75 % had symptomatic episodes of hypotension, in patients without cerebral circulation disorders in anamnesis only 54.6 %, (p < 0.05) in patients with myocardial infarction in 69.7 % of cases, without myocardial infarction – in 54.8 % of patients (p < 0.05). In persons with angina pectoris, symptomatic hypotension was detected in 66.9 %, without it-in 41.6 % (p < 0.05). The presence of diabetes was not associated with a significant increase in the likelihood of hypotension episodes. During the logistic regression analysis, angina pectoris and stroke were independent risk factors for symptomatic hypotension. Transient hypotension occurs in 57.8 % of patients receiving regular hypotensive therapy in 45.6 % of patients taking antihypertensive drugs only with increased blood pressure and 72.7 % not receiving hypotensive therapy (p < 0.05).
Conclusions. More than half of the surveyed patients over 40 years of age with hypertension suffer from episodes of symptomatic hypotension. Cardiovascular conditions, especially stroke and angina, are associated with an increase in the probability of symptomatic hypotensive episodes. The appearance of episodes of symptomatic hypotension can not always be explained by taking antihypertensive drugs. 

arterial hypertension, blood pressure variability, arterial hypotension, symptomatic hypotensive episodes, transient hypotension 

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